The patient eventually died of pulmonary edema and cardiac failure during the diuresis phase of an attack.ĭr. The unexplained shock and anasarca were followed several days later by a period of massive diuresis and diminution of peripheral edema. Clarkson’s index patient exemplifies SCLS: an otherwise healthy 34 year-old woman with sudden onset low-grade fevers, progressively declining blood pressure, rapid swelling of the face, arms, and legs, and rising hematocrit despite intravenous fluid resuscitation.
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